Silkworm chrysalis has very high nutritional content, rich in various vitamins, and essential amino acids for the human body, and its protein content is more than 50%, which is a high-quality animal quality. Through bio enzyme hydrolysis technology and process optimization, functional active peptides with specific biological activities are prepared.
NAMPT is nicotinamide phosphate drinking soup transferase, which widely exists in multiple tissues in the body and participates in the regulation of various physiological processes in the body. NAMPT is the rate-limiting enzyme in the main synthesis pathway of NAD+, which can catalyze the synthesis of NMN. NAD+ nicotinamide adenine dinucleotide, as the most important prosthetic group in the body, participates in cell proliferation and differentiation, energy metabolism, DNA repair, inflammation, etc. But the body's NAD+ levels are gradually depleted with age. Therefore, the rate-limiting enzyme NAMPT of the NAD+ salvage pathway is very important.
图片内容引用 Rajman et al, 2018, Cell Metabolism
Through synthetic biology and modern biotechnology methods, Escherichia coli, probiotics, yeast, potatoes, peanuts, silkworm chrysalis, etc. are used as the chassis cells to reconstruct the synthetic and metabolic pathways of active proteins such as SOD and small molecular substances and establish a large-scale production of biological activities. An innovative biological factory of materials with great industrial value.