What is SOD? Is it good for human body?
Superoxide dismutase (SOD) is an antioxidant metalloenzyme existing in organisms, which can catalyze the dismutation of superoxide anion radicals to generate oxygen and hydrogen peroxide. This enzyme is widely distributed and has been isolated from various organisms such as bacteria, fungi, algae, plants, protozoa, insects, fish and mammals so far. [1] Superoxide dismutase has anti-oxidation and anti-aging effects, and its mechanism of action is mainly to remove superoxide anion free radicals (O2-) which are harmful to the body. Superoxide dismutase has a unique curative effect on the treatment of diseases caused by superoxide free radicals (O2-), such as oxygen poisoning, acute inflammation, various autoimmune diseases, radiation diseases and senile cataracts, and is a promising New medicinal enzymes. Superoxide dismutase is being researched as an antiaging drug. [2] The main function of SOD is to catalyze the disproportionation of superoxide anion radicals into hydrogen peroxide and oxygen, and the generated superoxide anion radicals are normal metabolites in organisms. However, the accumulation of free radicals will cause lipid peroxidation in the cell membrane and cause membrane fission, resulting in cell damage or even death. SOD is the most important and best free radical scavenger in the organism, maintaining the metabolic balance of the body.[3]
In addition, SOD has a significant effect on the treatment of myocardial infarction, vascular heart disease, collagen disease, neonatal dyspnea syndrome, edema, emphysema, oxygen toxicity and other diseases, and can also treat psoriasis, dermatitis, eczema and pruritus and other skin diseases. As a superoxide anion free radical scavenger, SOD is widely used in delaying human aging, preventing diseases, improving human immunity, and as food and cosmetic additives. Since SOD was discovered as the first enzyme that uses superoxide anion as its substrate, it has fully proved its effective role in preventing and treating diseases related to superoxide free radicals. When the body produces too much superoxide anion or the concentration of SOD is low, the excess superoxide anion will cause disease, which can be effectively prevented and treated by giving exogenous SOD. [3] Studies have proved that adding SOD to food as a natural antioxidant can be used as a preservative. [4]
Clinical trials have shown that SOD is effective when taken orally and can be absorbed into the human body through the gastrointestinal tract. Therefore, SOD chewing gum, SOD buccal tablets, and oral liquids have emerged one after another, becoming one of the important ways to supplement SOD in vitro. [4]
Using the anti-oxidation and anti-aging effects of SOD, Angelo adds highly active SOD to dietary supplements, food, and drinks that humans consume daily to enhance the human's immune response and build an immune protection wall. Angelo also combines SOD with other dietary supplement raw materials to create a unique and world-leading core technology product. For example Angelo's products Immune-Pro, IifiniLife+, etc.
References：
1.Yuan Yunkai, Gu Mingyuan are editors; Sun Dawen, Ke Jiakang, and Zhao Xueshu are deputy editors. Dictionary of Science and Technology Society Biology: Zhejiang Education Press, 1991
2.Dong Liang, He Yongzhi, Wang Yuanliang, Dong Zhiyang. Advances in the application of superoxide dismutase (SOD)[J]. China Agricultural Science and Technology Herald. cnki.net. 2019 [reference date 2020-03-30]
3. Zhu Xiumin. Physiological activity of superoxide dismutase [J]. Contemporary Medicine. cnki.net. 2011 [reference date 2020-03-30]
4. Superoxide dismutase (SOD) and its application. Baidu Library. 2010 [reference date 2020-03-30]
